Product Data Sheet
Aprepitant-13C2,d2 (Major)
Catalog No. A47267
Aprepitant-13C2,d2 (Major) is a stable isotope-labeled variant of Aprepitant, a selective and high-affinity antagonist of the neurokinin 1 receptor with a dissociation constant (Kd) of 86 pM. This reagent is primarily utilized in pharmacokinetic studies and metabolic research. The 13C labeling allows for precise tracing and quantification in complex biological systems, facilitating a deeper understanding of Aprepitant's biochemical interactions and tissue distribution.
Chemical Information
| Catalog Num | A47267 |
|---|---|
| M. Wt | 538.42 |
| Formula | C2113C2H19D2F7N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217676-37-3 |
| Synonyms | MK-0869--13C2,d2; MK-869-13C2,d2; L-754030--13C2,d2 |
| SMILES | O=C1N[13C]([13CH2]N2CCO[C@@H]([C@@H]2C3=CC=C(C=C3)F)O[C@](C[2H])(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)[2H])=NN1 |
Biological Activity
| Description | Aprepitant-13C2,d2 (Major) is a stable isotope-labeled variant of Aprepitant, a selective and high-affinity antagonist of the neurokinin 1 receptor with a dissociation constant (Kd) of 86 pM. This reagent is primarily utilized in pharmacokinetic studies and metabolic research. The 13C labeling allows for precise tracing and quantification in complex biological systems, facilitating a deeper understanding of Aprepitant's biochemical interactions and tissue distribution. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
