Epoxyquinomicin B
Catalog No. A47291

Epoxyquinomicin B is an antibiotic sourced from Amycolatopsis sp., primarily targeting bacterial pathogens. It demonstrates significant inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida, and Staphylococcus aureus, with a minimum inhibitory concentration (MIC) ranging from 6.25 to 12.5 µg/mL. Additionally, Epoxyquinomicin B exhibits cytotoxic effects in L1210 cancer cells, with an IC50 of 16.3 µg/mL, and shows potential anti-inflammatory properties in models of collagen-induced arthritis. Its diverse biological activities render it a valuable tool for research in microbiology and cancer therapeutics.
Chemical Information
| Catalog Num | A47291 |
|---|---|
| M. Wt | 289.24 |
| Formula | C14H11NO6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 175448-32-5 |
| Synonyms | |
| SMILES | OC[C@]12[C@](C(C(NC(C3=C(C=CC=C3)O)=O)=CC2=O)=O)([H])O1 |
Biological Activity
| Description | Epoxyquinomicin B is an antibiotic sourced from Amycolatopsis sp., primarily targeting bacterial pathogens. It demonstrates significant inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida, and Staphylococcus aureus, with a minimum inhibitory concentration (MIC) ranging from 6.25 to 12.5 µg/mL. Additionally, Epoxyquinomicin B exhibits cytotoxic effects in L1210 cancer cells, with an IC50 of 16.3 µg/mL, and shows potential anti-inflammatory properties in models of collagen-induced arthritis. Its diverse biological activities render it a valuable tool for research in microbiology and cancer therapeutics. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


