Product Data Sheet
Valanimycin
Catalog No. A47450
Valanimycin is an antibiotic that targets Escherichia coli by interacting with DNA, effectively inhibiting bacterial growth. In addition to its antibacterial properties, Valanimycin demonstrates cytotoxic effects against mouse leukemia cell lines, including L1210, P388/S, and P388/ADR, with IC50 values of 0.79, 2.65, and 1.44 μg/mL, respectively. It also exhibits significant antitumor efficacy in models of ehrlich ascites tumors and L1210 cells in mice, making it a valuable compound for cancer research and antibiotic studies.
Chemical Information
| Catalog Num | A47450 |
|---|---|
| M. Wt | 172.18 |
| Formula | C7H12N2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 101961-60-8 |
| Synonyms | |
| SMILES | CC(C)C/[N+]([O-])=N/C(C(O)=O)=C |
Biological Activity
| Description | Valanimycin is an antibiotic that targets Escherichia coli by interacting with DNA, effectively inhibiting bacterial growth. In addition to its antibacterial properties, Valanimycin demonstrates cytotoxic effects against mouse leukemia cell lines, including L1210, P388/S, and P388/ADR, with IC50 values of 0.79, 2.65, and 1.44 μg/mL, respectively. It also exhibits significant antitumor efficacy in models of ehrlich ascites tumors and L1210 cells in mice, making it a valuable compound for cancer research and antibiotic studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
