Product Data Sheet

Propionylmaridomycin

Catalog No. A47489

main product photo
Propionylmaridomycin is a macrolide antibiotic that exhibits potent antibacterial activity. Following oral administration, it is rapidly absorbed and distributed to various tissues, demonstrating significantly higher concentration levels in the liver, kidneys, and lungs compared to plasma. Its superior antibacterial efficacy is particularly noted in pulmonary tissue, and it is predominantly excreted through feces. In metabolic studies on rats, Propionylmaridomycin is extensively metabolized, with 4''-depropionyl-9-propionylmaridomycin identified as the principal metabolite. This compound is valuable for research into antibiotic effectiveness and microbial resistance mechanisms.
Chemical Information
Catalog NumA47489
M. Wt914.08
FormulaC46H75NO17
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.35775-65-6
Synonyms
SMILESC[C@H]1[C@@H]([C@@](O)(C[C@H](O[C@@H]2[C@@H](N(C)C)[C@@H]([C@@H](O[C@@H]3[C@@H]([C@@H](CC(O[C@@H](C[C@@H]4[C@@H](/C=C/[C@@H](OC(CC)=O)[C@@H](C[C@@H]3CC=O)C)O4)C)=O)OC(CC)=O)OC)O[C@@H]2C)O)O1)C)OC(CC(C)C)=O
Biological Activity
DescriptionPropionylmaridomycin is a macrolide antibiotic that exhibits potent antibacterial activity. Following oral administration, it is rapidly absorbed and distributed to various tissues, demonstrating significantly higher concentration levels in the liver, kidneys, and lungs compared to plasma. Its superior antibacterial efficacy is particularly noted in pulmonary tissue, and it is predominantly excreted through feces. In metabolic studies on rats, Propionylmaridomycin is extensively metabolized, with 4''-depropionyl-9-propionylmaridomycin identified as the principal metabolite. This compound is valuable for research into antibiotic effectiveness and microbial resistance mechanisms.
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