Lactoquinomycin B
Catalog No. A47513

Lactoquinomycin B is an antitumor antibiotic that exerts its effects by targeting and inhibiting various cancer cell lines. It demonstrates significant activity against Gram-positive bacteria and exhibits weak effects on some Gram-negative bacteria, though it is ineffective against fungi. In cell viability assays, Lactoquinomycin B inhibits lymphoma L5178Y progenitor cells, as well as Adriamycin-resistant and Bleomycin-resistant cell lines, with observed ID50 values of 0.43, 0.21, and 0.19 μg/mL, respectively, indicating its potential utility in cancer research and antibiotic susceptibility studies.
Chemical Information
| Catalog Num | A47513 |
|---|---|
| M. Wt | 473.47 |
| Formula | C24H27NO9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 101342-94-3 |
| Synonyms | |
| SMILES | O=C1C23C(C(C4=C(O)C([C@H]5C[C@H]([C@@H]([C@H](O5)C)O)N(C)C)=CC=C41)=O)(C(OC6([H])C3([H])OC(C6)=O)C)O2 |
Biological Activity
| Description | Lactoquinomycin B is an antitumor antibiotic that exerts its effects by targeting and inhibiting various cancer cell lines. It demonstrates significant activity against Gram-positive bacteria and exhibits weak effects on some Gram-negative bacteria, though it is ineffective against fungi. In cell viability assays, Lactoquinomycin B inhibits lymphoma L5178Y progenitor cells, as well as Adriamycin-resistant and Bleomycin-resistant cell lines, with observed ID50 values of 0.43, 0.21, and 0.19 μg/mL, respectively, indicating its potential utility in cancer research and antibiotic susceptibility studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


