Product Data Sheet
Lactonamycin Z
Catalog No. A47517
Lactonamycin Z is an antitumor antibiotic that exerts its effects primarily through selective inhibition of tumor cell growth. It demonstrates significant cytotoxic activity against human cancer cell lines, including HMO2, MCF7, and Hep G2, with GI50 values of 1.9 μg/mL, 0.85 μg/mL, and 5.11 μg/mL, respectively. While it exhibits weak anti-Gram-positive bacterial activity, its primary research applications lie in the exploration of tumor cell mechanisms and potential therapeutic interventions in cancer treatment.
Chemical Information
| Catalog Num | A47517 |
|---|---|
| M. Wt | 585.51 |
| Formula | C28H27NO13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 709032-67-7 |
| Synonyms | |
| SMILES | CO[C@](OC1)(CC(O2)=O)[C@]2(C(C(C(C3=O)=CC4=C5)=C(O)C4=C6C(C(N(C6)C)=O)=C5O)=O)[C@@]13O[C@H]7C[C@H]([C@H]([C@@H](O7)C)O)O |
Biological Activity
| Description | Lactonamycin Z is an antitumor antibiotic that exerts its effects primarily through selective inhibition of tumor cell growth. It demonstrates significant cytotoxic activity against human cancer cell lines, including HMO2, MCF7, and Hep G2, with GI50 values of 1.9 μg/mL, 0.85 μg/mL, and 5.11 μg/mL, respectively. While it exhibits weak anti-Gram-positive bacterial activity, its primary research applications lie in the exploration of tumor cell mechanisms and potential therapeutic interventions in cancer treatment. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
