Product Data Sheet
Epoxyquinomicin A
Catalog No. A47602
Epoxyquinomicin A is an antibiotic derived from the bacterium Amycolatopsis sp., exhibiting significant antimicrobial activity against various pathogens including Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida, and Staphylococcus aureus, with minimum inhibitory concentrations (MIC) ranging from 3 to 12.5 µg/mL. Additionally, Epoxyquinomicin A demonstrates cytotoxic effects on cancer cell lines such as L1210, B16, and S180, with IC50 values between 2 and 8 µg/mL. Its anti-inflammatory properties have also been noted, particularly in models of collagen-induced arthritis, making it a valuable reagent for research in microbiology and oncology.
Chemical Information
| Catalog Num | A47602 |
|---|---|
| M. Wt | 323.69 |
| Formula | C14H10ClNO6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 175448-31-4 |
| Synonyms | |
| SMILES | OC[C@]12[C@](C(C(NC(C3=C(C(Cl)=CC=C3)O)=O)=CC2=O)=O)([H])O1 |
Biological Activity
| Description | Epoxyquinomicin A is an antibiotic derived from the bacterium Amycolatopsis sp., exhibiting significant antimicrobial activity against various pathogens including Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida, and Staphylococcus aureus, with minimum inhibitory concentrations (MIC) ranging from 3 to 12.5 µg/mL. Additionally, Epoxyquinomicin A demonstrates cytotoxic effects on cancer cell lines such as L1210, B16, and S180, with IC50 values between 2 and 8 µg/mL. Its anti-inflammatory properties have also been noted, particularly in models of collagen-induced arthritis, making it a valuable reagent for research in microbiology and oncology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
