4-O-Demethyl-11-deoxydoxorubicin
Catalog No. A47646

4-O-Demethyl-11-deoxydoxorubicin is an anthracycline antibiotic that primarily targets DNA, resulting in the inhibition of topoisomerase II activity. It exhibits significant cytotoxicity against various cancer cell lines, including HeLa cells. This compound is utilized in research focusing on anti-cancer mechanisms and the development of novel therapeutic strategies.
Chemical Information
| Catalog Num | A47646 |
|---|---|
| M. Wt | 513.49 |
| Formula | C26H27NO10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 81382-05-0 |
| Synonyms | |
| SMILES | O=C1C2=C(C(C3=C1C=C(C[C@@](C(CO)=O)(C[C@@H]4OC5O[C@H]([C@H]([C@H](C5)N)O)C)O)C4=C3O)=O)C(O)=CC=C2 |
Biological Activity
| Description | 4-O-Demethyl-11-deoxydoxorubicin is an anthracycline antibiotic that primarily targets DNA, resulting in the inhibition of topoisomerase II activity. It exhibits significant cytotoxicity against various cancer cell lines, including HeLa cells. This compound is utilized in research focusing on anti-cancer mechanisms and the development of novel therapeutic strategies. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


