Product Data Sheet

N-3-Hydroxydecanoyl-DL-homoserine lactone

Catalog No. A47678

main product photo
N-3-Hydroxydecanoyl-DL-homoserine lactone is a bacterial quorum-sensing molecule that primarily targets the transcription factor SdiA. It activates SdiA with an EC50 value of 0.6 µM, enabling the detection of N-acyl homoserine lactones (AHLs) in bacterial systems. This compound is particularly relevant for research into the regulation of gene expression in Salmonella enterica and other bacteria, providing insights into quorum sensing mechanisms and potential therapeutic strategies against bacterial infections.
Chemical Information
Catalog NumA47678
M. Wt271.35
FormulaC14H23NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.929222-14-0
Synonyms
SMILESCCCCCCCC(CC(NC1C(OCC1)=O)=O)O
Biological Activity
DescriptionN-3-Hydroxydecanoyl-DL-homoserine lactone is a bacterial quorum-sensing molecule that primarily targets the transcription factor SdiA. It activates SdiA with an EC50 value of 0.6 µM, enabling the detection of N-acyl homoserine lactones (AHLs) in bacterial systems. This compound is particularly relevant for research into the regulation of gene expression in Salmonella enterica and other bacteria, providing insights into quorum sensing mechanisms and potential therapeutic strategies against bacterial infections.
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