Product Data Sheet
Sapurimycin
Catalog No. A47726
Sapurimycin is an antitumor antibiotic derived from Streptomyces DO-116, belonging to the capramycin family. It demonstrates potent activity against Gram-positive bacteria and exhibits significant antitumor efficacy against leukemia P388 and sarcoma 180 in murine models. In vitro assays reveal that Sapurimycin induces single-strand breaks in supercoiled plasmid DNA, highlighting its potential utility in genomic studies and cancer research.
Chemical Information
| Catalog Num | A47726 |
|---|---|
| M. Wt | 462.41 |
| Formula | C25H18O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 132609-35-9 |
| Synonyms | Antibiotic DC 116 |
| SMILES | O=C(O)CC(C=C1C(C2=C3C(O)=CC=C2O)=O)=C(C(C=C([C@@]4(C)O[C@H]4/C=C\C)O5)=O)C5=C1C3=O |
Biological Activity
| Description | Sapurimycin is an antitumor antibiotic derived from Streptomyces DO-116, belonging to the capramycin family. It demonstrates potent activity against Gram-positive bacteria and exhibits significant antitumor efficacy against leukemia P388 and sarcoma 180 in murine models. In vitro assays reveal that Sapurimycin induces single-strand breaks in supercoiled plasmid DNA, highlighting its potential utility in genomic studies and cancer research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
