Product Data Sheet
10'-Desmethoxystreptonigrin
Catalog No. A47752
10'-Desmethoxystreptonigrin is an antibiotic that acts as an inhibitor of Ras Farnesyltransferase, exhibiting an IC50 of 21 μM. This compound demonstrates broad-spectrum antibacterial activity and shows antitumor effects against P388 leukemia, with an LD50 of 8.8 mg/kg indicating minimal cytotoxicity. It is a valuable reagent for research applications targeting antibiotic resistance and cancer therapeutics.
Chemical Information
| Catalog Num | A47752 |
|---|---|
| M. Wt | 476.44 |
| Formula | C24H20N4O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 136803-89-9 |
| Synonyms | |
| SMILES | NC(C(C(C=CC=C1OC)=C1O)=C2C)=C(C3=CC=C(C4=O)C(C(C(N)=C4OC)=O)=N3)N=C2C(O)=O |
Biological Activity
| Description | 10'-Desmethoxystreptonigrin is an antibiotic that acts as an inhibitor of Ras Farnesyltransferase, exhibiting an IC50 of 21 μM. This compound demonstrates broad-spectrum antibacterial activity and shows antitumor effects against P388 leukemia, with an LD50 of 8.8 mg/kg indicating minimal cytotoxicity. It is a valuable reagent for research applications targeting antibiotic resistance and cancer therapeutics. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
