Gatifloxacin-d4
Catalog No. A47835

Gatifloxacin-d4 is a deuterium-labeled derivative of the fluoroquinolone antibiotic Gatifloxacin, which primarily targets bacterial topoisomerases II. It exhibits broad-spectrum antibacterial activity, with IC50 values of 13.8 μg/mL against S. aureus topoisomerase IV and 0.109 μg/mL for E. coli DNA gyrase. This stable isotope-labeled compound is suitable for investigative research into bacterial infections, particularly in studies related to bacterial conjunctivitis.
Chemical Information
| Catalog Num | A47835 |
|---|---|
| M. Wt | 379.42 |
| Formula | C19H18D4FN3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1190043-25-4 |
| Synonyms | AM-1155-d4; BMS-206584-d4; PD135432-d4 |
| SMILES | FC1=CC2=C(C(OC)=C1N3C([2H])(C(NC([2H])(C3)[2H])C)[2H])N(C4CC4)C=C(C(O)=O)C2=O |
Biological Activity
| Description | Gatifloxacin-d4 is a deuterium-labeled derivative of the fluoroquinolone antibiotic Gatifloxacin, which primarily targets bacterial topoisomerases II. It exhibits broad-spectrum antibacterial activity, with IC50 values of 13.8 μg/mL against S. aureus topoisomerase IV and 0.109 μg/mL for E. coli DNA gyrase. This stable isotope-labeled compound is suitable for investigative research into bacterial infections, particularly in studies related to bacterial conjunctivitis. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


