Product Data Sheet
Taniborbactam hydrochloride
Catalog No. A47864
Taniborbactam hydrochloride is a reversible and selective β-lactamase inhibitor that targets various β-lactamase enzymes, demonstrating IC50 values ranging from 8 to 530 nM, with specific IC50s of 30 nM for KPC-2, 32 nM for AmpC, 42 nM for OXA-48, and 20 nM for VIM-2. This compound is effective against Gram-negative bacteria, making it a valuable tool in the study of antibiotic resistance mechanisms and the development of novel antibacterial strategies. Researchers can utilize Taniborbactam hydrochloride in investigations aimed at enhancing the efficacy of β-lactam antibiotics.
Chemical Information
| Catalog Num | A47864 |
|---|---|
| M. Wt | 462.18 |
| Formula | C19H30BCl2N3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2244235-49-0 |
| Synonyms | VNRX-5133 hydrochloride |
| SMILES | OC(C1=C(OB(O)[C@@H](NC(C[C@@H]2CC[C@@H](NCCN)CC2)=O)C3)C3=CC=C1)=O.[H]Cl.[H]Cl |
Biological Activity
| Description | Taniborbactam hydrochloride is a reversible and selective β-lactamase inhibitor that targets various β-lactamase enzymes, demonstrating IC50 values ranging from 8 to 530 nM, with specific IC50s of 30 nM for KPC-2, 32 nM for AmpC, 42 nM for OXA-48, and 20 nM for VIM-2. This compound is effective against Gram-negative bacteria, making it a valuable tool in the study of antibiotic resistance mechanisms and the development of novel antibacterial strategies. Researchers can utilize Taniborbactam hydrochloride in investigations aimed at enhancing the efficacy of β-lactam antibiotics. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
