Product Data Sheet
Vinaxanthone
Catalog No. A47903
Vinaxanthone is a selective inhibitor of semaphorin3A, phospholipase C (PLC), and FabI, exhibiting IC50 values of 0.1-0.2 μM for semaphorin3A and 0.9 mM for FabI. This compound also inhibits the substrate t-o-NAC thioester and the cofactor NADPH, with inhibition constants (Kis) of 3.1 μM and 1.0 μM, respectively. Vinaxanthone shows potential for combating infections caused by multidrug-resistant pathogens, making it a valuable tool for research in infectious diseases and drug resistance mechanisms.
Chemical Information
| Catalog Num | A47903 |
|---|---|
| M. Wt | 576.42 |
| Formula | C28H16O14 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 133293-89-7 |
| Synonyms | SM-345431 |
| SMILES | O=C(C(C(O)=C(C=C1OC=C2C3=C(C(C)=O)C4=C(C(C5=C(C(O)=O)C(O)=C(O)C=C5O4)=O)C=C3C(C)=O)O)=C1C2=O)O |
Biological Activity
| Description | Vinaxanthone is a selective inhibitor of semaphorin3A, phospholipase C (PLC), and FabI, exhibiting IC50 values of 0.1-0.2 μM for semaphorin3A and 0.9 mM for FabI. This compound also inhibits the substrate t-o-NAC thioester and the cofactor NADPH, with inhibition constants (Kis) of 3.1 μM and 1.0 μM, respectively. Vinaxanthone shows potential for combating infections caused by multidrug-resistant pathogens, making it a valuable tool for research in infectious diseases and drug resistance mechanisms. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
