Product Data Sheet

FA-Leu-Gly-Pro-Ala-OH

Catalog No. A47916

main product photo
FA-Leu-Gly-Pro-Ala-OH is a furylacryloyl-terminal tetrapeptide that acts as a substrate specifically for bacterial collagenase and spirochete metalloendopeptidase. It is selectively hydrolyzed at the Leu-Gly bond by spirochete collagenase, making it useful for studying peptide bond hydrolysis kinetics. This reagent can also be employed in detecting collagenase-mediated cleavage reactions using turbidimetry through absorbance reduction, providing valuable insights into enzyme activity and specificity.
Chemical Information
Catalog NumA47916
M. Wt476.52
FormulaC23H32N4O7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.78832-65-2
Synonyms
SMILESC(N[C@H](C(O)=O)C)(=O)[C@H]1N(C(CNC([C@@H](NC(C=CC2=CC=CO2)=O)CC(C)C)=O)=O)CCC1
Biological Activity
DescriptionFA-Leu-Gly-Pro-Ala-OH is a furylacryloyl-terminal tetrapeptide that acts as a substrate specifically for bacterial collagenase and spirochete metalloendopeptidase. It is selectively hydrolyzed at the Leu-Gly bond by spirochete collagenase, making it useful for studying peptide bond hydrolysis kinetics. This reagent can also be employed in detecting collagenase-mediated cleavage reactions using turbidimetry through absorbance reduction, providing valuable insights into enzyme activity and specificity.
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SHIPPING AND STORAGE
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