Product Data Sheet
(Rac)-SHIN2
Catalog No. A47953
(Rac)-SHIN2 is a pyrazolopyran derivative that functions as a selective inhibitor of serine hydroxymethyltransferase (SHMT). This compound demonstrates significant antibacterial activity, effectively targeting both vancomycin-susceptible and vanA-type vancomycin-resistant Enterococcus, while exhibiting low cytotoxicity towards Hep2 cells. The potential applications of (Rac)-SHIN2 include investigation into bacterial resistance mechanisms and the development of novel antibacterial therapeutics.
Chemical Information
| Catalog Num | A47953 |
|---|---|
| M. Wt | 406.48 |
| Formula | C23H26N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2204289-53-0 |
| Synonyms | |
| SMILES | N#CC(C1(C2=CC(C#CCCCO)=CC(CO)=C2)C(C)C)=C(N)OC3=C1C(C)=NN3 |
Biological Activity
| Description | (Rac)-SHIN2 is a pyrazolopyran derivative that functions as a selective inhibitor of serine hydroxymethyltransferase (SHMT). This compound demonstrates significant antibacterial activity, effectively targeting both vancomycin-susceptible and vanA-type vancomycin-resistant Enterococcus, while exhibiting low cytotoxicity towards Hep2 cells. The potential applications of (Rac)-SHIN2 include investigation into bacterial resistance mechanisms and the development of novel antibacterial therapeutics. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
