Product Data Sheet
TP4 (Nile tilapia piscidin)
Catalog No. A47997
TP4, an antimicrobial peptide derived from Nile tilapia, primarily targets bacterial membranes. It demonstrates significant inhibitory effects against a range of gram-positive and gram-negative bacteria, with minimum inhibitory concentrations (MIC) ranging from 0.03 to 10 μg/mL. Additionally, TP4 enhances immune responses and promotes intestinal health, while exhibiting antioxidant properties. Its potential anti-tumor effects are attributed to the induction of necrosis via mitochondrial dysfunction in cancer cells, making TP4 a valuable candidate for various biomedical research applications.
Chemical Information
| Catalog Num | A47997 |
|---|---|
| M. Wt | 2981.56 |
| Formula | C135H226N50O27 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1429184-62-2 |
| Synonyms | |
| SMILES | [C@@H](CC1=CN=CN1)(NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@H](CC3=CC=CC=C3)N)=O)[C@H](CC)C)=O)=O)C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CN=CN5)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)[C@H](CC)C)=O)C)=O)CCCCN)=O)=O)C)=O)CO)=O)=O)CC(C)C)=O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O |
Biological Activity
| Description | TP4, an antimicrobial peptide derived from Nile tilapia, primarily targets bacterial membranes. It demonstrates significant inhibitory effects against a range of gram-positive and gram-negative bacteria, with minimum inhibitory concentrations (MIC) ranging from 0.03 to 10 μg/mL. Additionally, TP4 enhances immune responses and promotes intestinal health, while exhibiting antioxidant properties. Its potential anti-tumor effects are attributed to the induction of necrosis via mitochondrial dysfunction in cancer cells, making TP4 a valuable candidate for various biomedical research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
