Product Data Sheet
PK150
Catalog No. A48061
PK150, an analogue of Sorafenib, is an antibiotic that demonstrates oral bioavailability and effective antibacterial activity against multiple pathogenic bacterial strains at submicromolar concentrations. Notably, PK150 exhibits inhibitory effects on Gram-positive bacteria, including Methicillin-sensitive Staphylococcus aureus (MSSA), Methicillin-resistant Staphylococcus aureus (MRSA), and Vancomycin intermediate Staphylococcus aureus (VISA), with minimum inhibitory concentrations (MICs) of 0.3 μM for MSSA and 0.3-1 μM for MRSA and VISA. This compound is suitable for research applications aimed at understanding bacterial resistance and developing novel antimicrobial therapies.
Chemical Information
| Catalog Num | A48061 |
|---|---|
| M. Wt | 394.68 |
| Formula | C15H8ClF5N2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2165324-62-7 |
| Synonyms | |
| SMILES | O=C(NC1=CC=C(OC(F)(F)O2)C2=C1)NC3=CC=C(Cl)C(C(F)(F)F)=C3 |
Biological Activity
| Description | PK150, an analogue of Sorafenib, is an antibiotic that demonstrates oral bioavailability and effective antibacterial activity against multiple pathogenic bacterial strains at submicromolar concentrations. Notably, PK150 exhibits inhibitory effects on Gram-positive bacteria, including Methicillin-sensitive Staphylococcus aureus (MSSA), Methicillin-resistant Staphylococcus aureus (MRSA), and Vancomycin intermediate Staphylococcus aureus (VISA), with minimum inhibitory concentrations (MICs) of 0.3 μM for MSSA and 0.3-1 μM for MRSA and VISA. This compound is suitable for research applications aimed at understanding bacterial resistance and developing novel antimicrobial therapies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
