Product Data Sheet
LL-37 amide
Catalog No. A48124
LL-37 amide is an antimicrobial peptide that selectively targets the formyl peptide receptor-like FPRL1. It demonstrates significant bactericidal activity against periodontal pathogens with an ED99 value of 8.5-8.7 μg/mL by inducing immune cell chemotaxis and disrupting bacterial cell membranes. Additionally, LL-37 amide modulates inflammatory responses by inhibiting the release of pro-inflammatory factors such as TNF-α and promotes angiogenesis. Its amidation modification enhances stability and reduces serum sensitivity. This reagent is valuable for research in infection-related diseases, including periodontal disease, deep tissue injuries, and wound healing.
Chemical Information
| Catalog Num | A48124 |
|---|---|
| M. Wt | 4492.28 |
| Formula | C205H341N61O52 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 597562-32-8 |
| Synonyms | |
| SMILES |
Biological Activity
| Description | LL-37 amide is an antimicrobial peptide that selectively targets the formyl peptide receptor-like FPRL1. It demonstrates significant bactericidal activity against periodontal pathogens with an ED99 value of 8.5-8.7 μg/mL by inducing immune cell chemotaxis and disrupting bacterial cell membranes. Additionally, LL-37 amide modulates inflammatory responses by inhibiting the release of pro-inflammatory factors such as TNF-α and promotes angiogenesis. Its amidation modification enhances stability and reduces serum sensitivity. This reagent is valuable for research in infection-related diseases, including periodontal disease, deep tissue injuries, and wound healing. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
