Product Data Sheet

LpxH-IN-AZ1

Catalog No. A48212

main product photo
LpxH-IN-AZ1 is a sulfonyl piperazine compound that functions as a potent inhibitor of UDP-2,3-diacylglucosamine pyrophosphate hydrolase (LpxH). This compound demonstrates significant inhibitory activity against Klebsiella pneumoniae LpxH, achieving an IC50 value of 0.36 μM. LpxH-IN-AZ1 is valuable for research applications targeting antibiotic drug development and bacterial resistance mechanisms.
Chemical Information
Catalog NumA48212
M. Wt453.48
FormulaC21H22F3N3O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.901260-40-0
Synonyms
SMILESCC(N1CCC2=C1C=CC(S(=O)(N3CCN(C4=CC=CC(C(F)(F)F)=C4)CC3)=O)=C2)=O
Biological Activity
DescriptionLpxH-IN-AZ1 is a sulfonyl piperazine compound that functions as a potent inhibitor of UDP-2,3-diacylglucosamine pyrophosphate hydrolase (LpxH). This compound demonstrates significant inhibitory activity against Klebsiella pneumoniae LpxH, achieving an IC50 value of 0.36 μM. LpxH-IN-AZ1 is valuable for research applications targeting antibiotic drug development and bacterial resistance mechanisms.
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SHIPPING AND STORAGE
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