Product Data Sheet
UNC10201652
Catalog No. A48263
UNC10201652 is a potent inhibitor of bacterial β-glucuronidase, specifically targeting Loop 1 (L1) in gut microbiota, with an IC50 value of 0.117 μM for E. coli β-glucuronidase. This compound effectively blocks the processing of SN-38 glucuronide, predominantly in individuals with a high abundance of L1 GUS enzymes in their fecal microbiota. Its application is of particular interest in studying gut microbiome interactions and drug metabolism.
Chemical Information
| Catalog Num | A48263 |
|---|---|
| M. Wt | 411.52 |
| Formula | C20H25N7OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 372495-52-8 |
| Synonyms | |
| SMILES | C1(N=NN=C2N3CCNCC3)=C2SC4=C1C(CCCC5)=C5C(N6CCOCC6)=N4 |
Biological Activity
| Description | UNC10201652 is a potent inhibitor of bacterial β-glucuronidase, specifically targeting Loop 1 (L1) in gut microbiota, with an IC50 value of 0.117 μM for E. coli β-glucuronidase. This compound effectively blocks the processing of SN-38 glucuronide, predominantly in individuals with a high abundance of L1 GUS enzymes in their fecal microbiota. Its application is of particular interest in studying gut microbiome interactions and drug metabolism. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
