Product Data Sheet
Nornidulin
Catalog No. A48371
Nornidulin is a depsidone derived from Aspergillus nidulans, exhibiting significant antibacterial activity against Mycobacterium tuberculosis and Mycobacterium ranoe, as well as antifungal effects against Trichophyton tonsurans and Microsporum audouini. Additionally, it demonstrates potent inhibition of methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 2 μg/mL. Furthermore, Nornidulin displays cytotoxicity in MOLT-3 cells with an IC50 value of 35.7 μM, while exhibiting lower toxicity against HuCCA-1, HepG2, and A549 cell lines.
Chemical Information
| Catalog Num | A48371 |
|---|---|
| M. Wt | 429.68 |
| Formula | C19H15Cl3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 33403-37-1 |
| Synonyms | |
| SMILES | CC1=C(C(Cl)=C(C2=C1OC(C3=C(O2)C(Cl)=C(C(Cl)=C3C)O)=O)/C(C)=C\C)O |
Biological Activity
| Description | Nornidulin is a depsidone derived from Aspergillus nidulans, exhibiting significant antibacterial activity against Mycobacterium tuberculosis and Mycobacterium ranoe, as well as antifungal effects against Trichophyton tonsurans and Microsporum audouini. Additionally, it demonstrates potent inhibition of methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 2 μg/mL. Furthermore, Nornidulin displays cytotoxicity in MOLT-3 cells with an IC50 value of 35.7 μM, while exhibiting lower toxicity against HuCCA-1, HepG2, and A549 cell lines. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
