Product Data Sheet
Griselimycin
Catalog No. A48440
Griselimycin is a cyclic lipopeptide that functions as a bacterial inhibitor by specifically binding to the sliding clamp of bacterial DNA polymerase, while exhibiting no interaction with human proliferating cell nuclear antigen (PCNA). This compound demonstrates potent antibacterial activity against Mycobacterium tuberculosis, including drug-resistant strains, and various Gram-negative bacteria. Griselimycin is useful in research applications focused on bacterial DNA replication and the development of new antibacterial therapeutics.
Chemical Information
| Catalog Num | A48440 |
|---|---|
| M. Wt | 1113.43 |
| Formula | C57H96N10O12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 26034-16-2 |
| Synonyms | |
| SMILES | [H][C@@]12CCCN1C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@]1([H])C[C@@H](C)CN1C(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)OC(=O)CNC(=O)[C@@H](CC(C)C)N(C)C2=O)N(C)C(=O)[C@@H]1C[C@@H](C)CN1C(=O)[C@H](C(C)C)N(C)C(C)=O |@:73| |
Biological Activity
| Description | Griselimycin is a cyclic lipopeptide that functions as a bacterial inhibitor by specifically binding to the sliding clamp of bacterial DNA polymerase, while exhibiting no interaction with human proliferating cell nuclear antigen (PCNA). This compound demonstrates potent antibacterial activity against Mycobacterium tuberculosis, including drug-resistant strains, and various Gram-negative bacteria. Griselimycin is useful in research applications focused on bacterial DNA replication and the development of new antibacterial therapeutics. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
