Product Data Sheet
MRL-494
Catalog No. A48647
MRL-494 is an antibacterial agent that targets the β-barrel assembly machine A (BamA), effectively overcoming efflux mechanisms and the outer membrane permeability barrier. It demonstrates significant antibacterial activity, with a minimum inhibitory concentration (MIC) of 12.5 μM against Staphylococcus aureus (COL) and 25 μM against Escherichia coli (JCM158). This compound is valuable for research into novel antibacterial therapies and mechanisms of resistance in both Gram-positive and Gram-negative bacteria.
Chemical Information
| Catalog Num | A48647 |
|---|---|
| M. Wt | 622.66 |
| Formula | C26H35FN16O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2434898-43-6 |
| Synonyms | |
| SMILES | FC1=CC=C(C2=NN(CC(N[C@@H]3CC[C@H](NC4=NC(NC(C5CC5)CC(NC(N)=N)=O)=NC(NC(N)=N)=N4)CC3)=O)N=N2)C=C1 |
Biological Activity
| Description | MRL-494 is an antibacterial agent that targets the β-barrel assembly machine A (BamA), effectively overcoming efflux mechanisms and the outer membrane permeability barrier. It demonstrates significant antibacterial activity, with a minimum inhibitory concentration (MIC) of 12.5 μM against Staphylococcus aureus (COL) and 25 μM against Escherichia coli (JCM158). This compound is valuable for research into novel antibacterial therapies and mechanisms of resistance in both Gram-positive and Gram-negative bacteria. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
