Product Data Sheet
K11
Catalog No. A48708
K11 is a stable antimicrobial peptide that exhibits significant activity against multidrug-resistant and extensively drug-resistant K. pneumoniae isolates, demonstrating a minimum inhibitory concentration (MIC) range of 8-512 μg/mL. This peptide not only inhibits bacterial biofilm formation but also displays synergistic effects when combined with various antibiotics, including chloramphenicol, meropenem, and rifampicin, enhancing the efficacy against drug-resistant strains. K11 maintains high thermal stability and demonstrates effective function across a broad pH range, making it a valuable tool for antimicrobial research and therapeutic applications.
Chemical Information
| Catalog Num | A48708 |
|---|---|
| M. Wt | 2493.09 |
| Formula | C123H198N32O23 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1398109-79-9 |
| Synonyms | |
| SMILES | C([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)CCCCN)=O)CCCCN)=O)C)=O)CO)=O)=O)CC(C)C)=O)=O)CCCCN)=O)CCCCN)=O)[C@@H](C)O)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)[C@H](CC)C)=O)=O)CO)=O)CCCCN)=O)NC([C@H](CCCCN)N)=O)C=5C=6C(NC5)=CC=CC6 |
Biological Activity
| Description | K11 is a stable antimicrobial peptide that exhibits significant activity against multidrug-resistant and extensively drug-resistant K. pneumoniae isolates, demonstrating a minimum inhibitory concentration (MIC) range of 8-512 μg/mL. This peptide not only inhibits bacterial biofilm formation but also displays synergistic effects when combined with various antibiotics, including chloramphenicol, meropenem, and rifampicin, enhancing the efficacy against drug-resistant strains. K11 maintains high thermal stability and demonstrates effective function across a broad pH range, making it a valuable tool for antimicrobial research and therapeutic applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
