Product Data Sheet

8-Br-GTP

Catalog No. A48754

main product photo
8-Br-GTP is a GTP analog that serves as a competitive inhibitor of FtsZ polymerization and GTPase activity, exhibiting a Ki value of 31.8 μM. This compound demonstrates antibacterial properties and can be utilized for nucleic acid modification in various research applications, particularly in the study of bacterial cell division and antibiotic resistance mechanisms.
Chemical Information
Catalog NumA48754
M. Wt602.08
FormulaC10H15BrN5O14P3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.23197-98-0
Synonyms8-Bromoguanosine-5'-triphosphate
SMILESO=P(O)(O)OP(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(Br)=NC3=C2NC(N)=NC3=O)O1)(O)=O)(O)=O
Biological Activity
Description8-Br-GTP is a GTP analog that serves as a competitive inhibitor of FtsZ polymerization and GTPase activity, exhibiting a Ki value of 31.8 μM. This compound demonstrates antibacterial properties and can be utilized for nucleic acid modification in various research applications, particularly in the study of bacterial cell division and antibiotic resistance mechanisms.
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