Product Data Sheet
DRGN-1
Catalog No. A48929
DRGN-1 is an antimicrobial peptide that demonstrates powerful antimicrobial and anti-biofilm properties, effectively targeting both Gram-negative and Gram-positive bacteria with an EC50 range of 0.50-4.62 μM. Its mechanism of action involves the disruption of bacterial membrane permeability and a slight depolarization of membrane potential. DRGN-1 also inhibits biofilm formation in both single and mixed species, including Pseudomonas aeruginosa and Staphylococcus aureus. Additionally, it has been shown to significantly enhance the healing process in uninfected and mixed biofilm-infected mouse wounds, making it a valuable reagent for research on infections.
Chemical Information
| Catalog Num | A48929 |
|---|---|
| M. Wt | 1535.92 |
| Formula | C71H130N20O17 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2173394-02-8 |
| Synonyms | |
| SMILES |
Biological Activity
| Description | DRGN-1 is an antimicrobial peptide that demonstrates powerful antimicrobial and anti-biofilm properties, effectively targeting both Gram-negative and Gram-positive bacteria with an EC50 range of 0.50-4.62 μM. Its mechanism of action involves the disruption of bacterial membrane permeability and a slight depolarization of membrane potential. DRGN-1 also inhibits biofilm formation in both single and mixed species, including Pseudomonas aeruginosa and Staphylococcus aureus. Additionally, it has been shown to significantly enhance the healing process in uninfected and mixed biofilm-infected mouse wounds, making it a valuable reagent for research on infections. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
