Product Data Sheet
Oncocin
Catalog No. A48933
Oncocin is an antibacterial peptide belonging to the proline-rich antimicrobial peptide (PrAMP) class. It exhibits potent activity against Gram-negative bacteria, with minimal inhibitory concentrations (MIC) ranging from 0.125 to 8 μg/mL against various strains and clinical isolates of Enterobacteriaceae and non-fermenters. Oncocin targets the substrate-binding domain of the chaperone DnaK, leading to protein misfolding and aggregation, ultimately resulting in bacterial cell death. This mechanism makes Oncocin valuable for research into bacterial resistance and antimicrobial therapies.
Chemical Information
| Catalog Num | A48933 |
|---|---|
| M. Wt | 2389.81 |
| Formula | C109H177N37O24 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1235497-90-1 |
| Synonyms | |
| SMILES | C(=O)([C@H]1N(C([C@@H](NC(=O)[C@H]2N(C([C@@H](NC(=O)[C@H]3N(C([C@@H](NC([C@@H](NC(=O)[C@H]4N(C(=O)[C@H]5N(C([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CC(O)=O)=O)CCCCN)=O)CCC5)CCC4)CC6=CC=C(O)C=C6)=O)CC(C)C)=O)CCC3)CCCNC(=N)N)=O)CCC2)CCCNC(=N)N)=O)CCC1)N7[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC8=CC=C(O)C=C8)C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CC(N)=O)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC7 |
Biological Activity
| Description | Oncocin is an antibacterial peptide belonging to the proline-rich antimicrobial peptide (PrAMP) class. It exhibits potent activity against Gram-negative bacteria, with minimal inhibitory concentrations (MIC) ranging from 0.125 to 8 μg/mL against various strains and clinical isolates of Enterobacteriaceae and non-fermenters. Oncocin targets the substrate-binding domain of the chaperone DnaK, leading to protein misfolding and aggregation, ultimately resulting in bacterial cell death. This mechanism makes Oncocin valuable for research into bacterial resistance and antimicrobial therapies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
