Product Data Sheet
Lascufloxacin hydrochloride
Catalog No. A48947
Lascufloxacin hydrochloride is a potent antibacterial compound that targets bacterial DNA gyrase and topoisomerase IV, exhibiting broad-spectrum activity against diverse clinical isolates. It demonstrates robust efficacy against Gram-positive bacteria, outperforming other quinolone derivatives. Notably, Lascufloxacin hydrochloride shows incomplete cross-resistance to certain quinolone-resistant strains, making it a valuable candidate for further investigation. Its ability to inhibit both wild-type and mutated target enzymes underscores its potential in tackling resistant bacterial infections in research settings.
Chemical Information
| Catalog Num | A48947 |
|---|---|
| M. Wt | 475.89 |
| Formula | C21H25ClF3N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1433857-09-0 |
| Synonyms | KRP-AM1977 hydrochloride |
| SMILES | O=C(O)C1=CN(C2=C(C1=O)C=C(C(N3C[C@@H]([C@@H](C3)F)CNC4CC4)=C2OC)F)CCF.Cl |
Biological Activity
| Description | Lascufloxacin hydrochloride is a potent antibacterial compound that targets bacterial DNA gyrase and topoisomerase IV, exhibiting broad-spectrum activity against diverse clinical isolates. It demonstrates robust efficacy against Gram-positive bacteria, outperforming other quinolone derivatives. Notably, Lascufloxacin hydrochloride shows incomplete cross-resistance to certain quinolone-resistant strains, making it a valuable candidate for further investigation. Its ability to inhibit both wild-type and mutated target enzymes underscores its potential in tackling resistant bacterial infections in research settings. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
