Product Data Sheet
WLBU2
Catalog No. A49024
WLBU2 is an engineered cationic antimicrobial peptide (eCAP) that targets bacterial membranes, demonstrating rapid bactericidal activity. It exhibits minimum inhibitory concentration (MIC) values of ≤ 10 μM against a range of Gram-negative and Gram-positive bacteria, including MRSA and vancomycin-resistant enterococci. WLBU2 effectively prevents biofilm formation by Pseudomonas aeruginosa and retains antimicrobial efficacy in challenging environments such as high salinity and low pH, without compromising human airway epithelial cell viability. This reagent is valuable for research investigating cystic fibrosis and Pseudomonas aeruginosa infections.
Chemical Information
| Catalog Num | A49024 |
|---|---|
| M. Wt | 3400.11 |
| Formula | C151H260N66O25 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 847061-43-2 |
| Synonyms | |
| SMILES | C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)=O)C(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@@H](C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCNC(=N)N)=O)C(C)C)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)C(C)C)=O)[C@H](C)C)=O)CCCNC(=N)N)=O)[C@@H](C)C)=O)C(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@H](C)C)=O)C=5C=6C(NC5)=CC=CC6 |
Biological Activity
| Description | WLBU2 is an engineered cationic antimicrobial peptide (eCAP) that targets bacterial membranes, demonstrating rapid bactericidal activity. It exhibits minimum inhibitory concentration (MIC) values of ≤ 10 μM against a range of Gram-negative and Gram-positive bacteria, including MRSA and vancomycin-resistant enterococci. WLBU2 effectively prevents biofilm formation by Pseudomonas aeruginosa and retains antimicrobial efficacy in challenging environments such as high salinity and low pH, without compromising human airway epithelial cell viability. This reagent is valuable for research investigating cystic fibrosis and Pseudomonas aeruginosa infections. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
