Product Data Sheet
DS-8587
Catalog No. A49090
DS-8587 is a novel fluoroquinolone designed as a bacterial inhibitor, demonstrating significant antibacterial activity against amoxicillin-resistant Bacillus strains. Its minimum inhibitory concentration (MIC) values outperform those of ciprofloxacin and levofloxacin, while exhibiting reduced susceptibility to efflux pump-mediated resistance mechanisms such as adeA/adeB/adeC and abeM. Additionally, DS-8587 has a lower single-step mutation frequency compared to ciprofloxacin, positioning it as a promising therapeutic candidate for the treatment of amoxicillin-resistant Bacillus infections.
Chemical Information
| Catalog Num | A49090 |
|---|---|
| M. Wt | 493.90 |
| Formula | C21H27ClF3N3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1356918-39-2 |
| Synonyms | |
| SMILES | CC1=C2N([C@H]3[C@H](C3)F)C=C(C(C2=CC(F)=C1N4C[C@@]5([C@](C4)(CCC5)N)F)=O)C(O)=O.Cl.O.O |
Biological Activity
| Description | DS-8587 is a novel fluoroquinolone designed as a bacterial inhibitor, demonstrating significant antibacterial activity against amoxicillin-resistant Bacillus strains. Its minimum inhibitory concentration (MIC) values outperform those of ciprofloxacin and levofloxacin, while exhibiting reduced susceptibility to efflux pump-mediated resistance mechanisms such as adeA/adeB/adeC and abeM. Additionally, DS-8587 has a lower single-step mutation frequency compared to ciprofloxacin, positioning it as a promising therapeutic candidate for the treatment of amoxicillin-resistant Bacillus infections. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
