Product Data Sheet
NDM-1 inhibitor-2
Catalog No. A49347
NDM-1 inhibitor-2 is a selective inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) that effectively inhibits NDM-1 enzymatic activity. This compound demonstrates significant antibacterial activity against drug-resistant bacterial strains that overexpress NDM-1, providing insights into overcoming resistance mechanisms. Additionally, NDM-1 inhibitor-2 can enhance the efficacy of the carbapenem antibiotic meropenem, resulting in a synergistic effect that supports research in antimicrobial therapy and resistance management.
Chemical Information
| Catalog Num | A49347 |
|---|---|
| M. Wt | 285.16 |
| Formula | C9H9BrN4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 665013-76-3 |
| Synonyms | |
| SMILES | S=C1NN=CN1NCC2=CC=CC(Br)=C2 |
Biological Activity
| Description | NDM-1 inhibitor-2 is a selective inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) that effectively inhibits NDM-1 enzymatic activity. This compound demonstrates significant antibacterial activity against drug-resistant bacterial strains that overexpress NDM-1, providing insights into overcoming resistance mechanisms. Additionally, NDM-1 inhibitor-2 can enhance the efficacy of the carbapenem antibiotic meropenem, resulting in a synergistic effect that supports research in antimicrobial therapy and resistance management. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
