Product Data Sheet

BDM91288

Catalog No. A49411

main product photo
BDM91288 is an orally active inhibitor of the AcrB efflux pump, derived from pyridinium piperazine. This compound demonstrates significant potential to enhance the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infections, as evidenced by mouse model studies. BDM91288 serves as a valuable tool for research focused on combating antibiotic resistance and improving the effectiveness of existing antimicrobial therapies.
Chemical Information
Catalog NumA49411
M. Wt331.84
FormulaC17H22ClN5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2892824-53-0
Synonyms
SMILESClC(C=C(C=C(N1CCNCC1)C=C2)C2=N3)=C3N4CCNCC4
Biological Activity
DescriptionBDM91288 is an orally active inhibitor of the AcrB efflux pump, derived from pyridinium piperazine. This compound demonstrates significant potential to enhance the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infections, as evidenced by mouse model studies. BDM91288 serves as a valuable tool for research focused on combating antibiotic resistance and improving the effectiveness of existing antimicrobial therapies.
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