Product Data Sheet
BPH-1358 free base
Catalog No. A49562
BPH-1358 free base is a potent inhibitor of human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS), exhibiting IC50 values of 1.8 μM and 110 nM, respectively. This compound demonstrates significant antibacterial activity against Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of approximately 250 ng/mL. BPH-1358 free base is suitable for research applications aimed at understanding bacterial resistance mechanisms and developing novel antibacterial strategies.
Chemical Information
| Catalog Num | A49562 |
|---|---|
| M. Wt | 528.60 |
| Formula | C32H28N6O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 801985-13-7 |
| Synonyms | NSC50460 free base |
| SMILES | O=C(C1=CC=C(C2=CC=C(C(NC3=CC=CC(C4=NCCN4)=C3)=O)C=C2)C=C1)NC5=CC=CC(C6=NCCN6)=C5 |
Biological Activity
| Description | BPH-1358 free base is a potent inhibitor of human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS), exhibiting IC50 values of 1.8 μM and 110 nM, respectively. This compound demonstrates significant antibacterial activity against Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of approximately 250 ng/mL. BPH-1358 free base is suitable for research applications aimed at understanding bacterial resistance mechanisms and developing novel antibacterial strategies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
