Antitubercular agent-57
Catalog No. A50154

Antitubercular agent-57 is a selective antimycobacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant efficacy against both drug-sensitive and multidrug-resistant strains, including extensively drug-resistant variants, while maintaining low toxicity towards mammalian cell lines, such as hepatocytes. Antitubercular agent-57 exhibits no cross-resistance with established first and second-line antitubercular agents and shows no antimicrobial activity against Gram-positive and Gram-negative bacteria or fungal strains. This reagent is valuable for research focused on tuberculosis and multidrug-resistant tuberculosis.
Chemical Information
| Catalog Num | A50154 |
|---|---|
| M. Wt | 276.29 |
| Formula | C13H16N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 461431-74-3 |
| Synonyms | |
| SMILES | CC(C)(C)C(C=C1)=CC=C1OC2=NC([N+]([O-])=O)=NN2C |
Biological Activity
| Description | Antitubercular agent-57 is a selective antimycobacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant efficacy against both drug-sensitive and multidrug-resistant strains, including extensively drug-resistant variants, while maintaining low toxicity towards mammalian cell lines, such as hepatocytes. Antitubercular agent-57 exhibits no cross-resistance with established first and second-line antitubercular agents and shows no antimicrobial activity against Gram-positive and Gram-negative bacteria or fungal strains. This reagent is valuable for research focused on tuberculosis and multidrug-resistant tuberculosis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


