Product Data Sheet
Ilicicolin F
Catalog No. A50191
Ilicicolin F is a fungal metabolite that primarily targets bacterial oxidases, specifically inhibiting T. vivax alternative oxidase and E. coli ubiquinol oxidase cytochrome bo, with IC50 values of 0.43 and 0.37 μM, respectively. It exhibits antifungal activity against Aspergillus fumigatus and Candida albicans, demonstrating minimum inhibitory concentrations ranging from 1.66 to 13.33 μg/mL. Additionally, Ilicicolin F displays significant cytotoxicity in HeLa cells, with an EC50 value of 0.003 μg/mL, making it a potent candidate for research in microbial and cancer studies.
Chemical Information
| Catalog Num | A50191 |
|---|---|
| M. Wt | 462.96 |
| Formula | C25H31ClO6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 22738-98-3 |
| Synonyms | LL-Z 1272ζ |
| SMILES | O=CC1=C(C)C(Cl)=C(O)C(C/C=C(C)/C=C/[C@@]2(C)[C@H](C)[C@@H](OC(C)=O)CC([C@@H]2C)=O)=C1O |
Biological Activity
| Description | Ilicicolin F is a fungal metabolite that primarily targets bacterial oxidases, specifically inhibiting T. vivax alternative oxidase and E. coli ubiquinol oxidase cytochrome bo, with IC50 values of 0.43 and 0.37 μM, respectively. It exhibits antifungal activity against Aspergillus fumigatus and Candida albicans, demonstrating minimum inhibitory concentrations ranging from 1.66 to 13.33 μg/mL. Additionally, Ilicicolin F displays significant cytotoxicity in HeLa cells, with an EC50 value of 0.003 μg/mL, making it a potent candidate for research in microbial and cancer studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
