Product Data Sheet
Reveromycin D
Catalog No. A50255
Reveromycin D is a bacterial metabolite derived from Streptomyces, known for its ability to inhibit EGF-induced mitogenic activity in Balb/MK cells. This compound exhibits pH-dependent antifungal activity against Candida albicans, with minimum inhibitory concentrations (MICs) of 2 μg/mL at pH 3 and >500 μg/mL at pH 7.4. Additionally, Reveromycin D demonstrates significant antiproliferative effects on KB and K562 cancer cell lines, with IC50 values of 1.6 and 1.3 μg/mL, respectively, making it valuable for research in cell signaling and cancer therapeutics.
Chemical Information
| Catalog Num | A50255 |
|---|---|
| M. Wt | 674.82 |
| Formula | C₃₇H₅₄O₁₁ |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 144860-70-8 |
| Synonyms | |
| SMILES | CCCCC[C@@]1(C[C@@H](O[C@@]2(C1)CC[C@@H]([C@H](O2)C/C=C(\C)/C=C/[C@@H]([C@@H](C)/C=C/C(=O)O)O)C)/C=C/C(=C/C(=O)O)/C)OC(=O)CCC(=O)O |
Biological Activity
| Description | Reveromycin D is a bacterial metabolite derived from Streptomyces, known for its ability to inhibit EGF-induced mitogenic activity in Balb/MK cells. This compound exhibits pH-dependent antifungal activity against Candida albicans, with minimum inhibitory concentrations (MICs) of 2 μg/mL at pH 3 and >500 μg/mL at pH 7.4. Additionally, Reveromycin D demonstrates significant antiproliferative effects on KB and K562 cancer cell lines, with IC50 values of 1.6 and 1.3 μg/mL, respectively, making it valuable for research in cell signaling and cancer therapeutics. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
