Product Data Sheet

CAP 3

Catalog No. A50565

main product photo
CAP 3 is a cholic acid-peptide conjugate that acts as an effective antibacterial agent targeting Gram-negative bacteria. It demonstrates potent antibacterial activity with minimum inhibitory concentration (MIC99) values of 8 μM, 16 μM, and 16 μM against E. coli, Klebsiella pneumoniae, and Acinetobacter baumannii, respectively. CAP 3 functions by disrupting the structural integrity of bacterial lipopolysaccharide (LPS) outer membranes, leading to rapid bacterial cell death. Additionally, it inhibits biofilm formation and shows efficacy against drug-resistant strains, making it valuable for addressing persistent bacterial infections in research settings.
Chemical Information
Catalog NumA50565
M. Wt967.24
FormulaC52H82N6O11
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2292123-03-4
Synonyms
SMILESCC(C)[C@H](N)C(NCC(O[C@H]1[C@]2([H])[C@@](C[C@@H]([C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCC(OCC4=CC=CC=C4)=O)C)OC(CNC([C@@H](N)C(C)C)=O)=O)([H])[C@@]5([C@](C[C@@H](CC5)OC(CNC([C@@H](N)C(C)C)=O)=O)([H])C1)C)=O)=O
Biological Activity
DescriptionCAP 3 is a cholic acid-peptide conjugate that acts as an effective antibacterial agent targeting Gram-negative bacteria. It demonstrates potent antibacterial activity with minimum inhibitory concentration (MIC99) values of 8 μM, 16 μM, and 16 μM against E. coli, Klebsiella pneumoniae, and Acinetobacter baumannii, respectively. CAP 3 functions by disrupting the structural integrity of bacterial lipopolysaccharide (LPS) outer membranes, leading to rapid bacterial cell death. Additionally, it inhibits biofilm formation and shows efficacy against drug-resistant strains, making it valuable for addressing persistent bacterial infections in research settings.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.