Product Data Sheet

Negamycin

Catalog No. A50572

main product photo
Negamycin is a bacterial inhibitor that targets protein synthesis by binding to the head domain of the bacterial ribosomal small subunit. This interaction disrupts normal translation, leading to cell death and enhancing the misreading of near-cognate codons. Negamycin is valuable for research applications focused on understanding antibiotic mechanisms and bacterial resistance.
Chemical Information
Catalog NumA50572
M. Wt248.28
FormulaC9H20N4O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.33404-78-3
Synonyms
SMILESNC[C@H](O)C[C@@H](N)CC(NN(C)CC(O)=O)=O
Biological Activity
DescriptionNegamycin is a bacterial inhibitor that targets protein synthesis by binding to the head domain of the bacterial ribosomal small subunit. This interaction disrupts normal translation, leading to cell death and enhancing the misreading of near-cognate codons. Negamycin is valuable for research applications focused on understanding antibiotic mechanisms and bacterial resistance.
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