Product Data Sheet

SIRT1-IN-1

Catalog No. A50659

main product photo
SIRT1-IN-1 is a selective inhibitor of SIRT1, exhibiting an IC50 of 0.205 μM. In addition to its primary target, it also inhibits SIRT2 with an IC50 of 11.5 μM. This indole compound demonstrates antiviral activity, particularly against cytomegalovirus (CMV), making it a valuable tool for research into SIRT1-related pathways and antiviral applications.
Chemical Information
Catalog NumA50659
M. Wt228.29
FormulaC14H16N2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.352554-02-0
Synonyms
SMILESO=C(C1C(NC2=C3C=C(C)C=C2)=C3CCC1)N
Biological Activity
DescriptionSIRT1-IN-1 is a selective inhibitor of SIRT1, exhibiting an IC50 of 0.205 μM. In addition to its primary target, it also inhibits SIRT2 with an IC50 of 11.5 μM. This indole compound demonstrates antiviral activity, particularly against cytomegalovirus (CMV), making it a valuable tool for research into SIRT1-related pathways and antiviral applications.
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SHIPPING AND STORAGE
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