Product Data Sheet

Fomivirsen

Catalog No. A50660

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Fomivirsen is an antisense phosphorothioate oligonucleotide that acts as a cytomegalovirus (CMV) inhibitor by selectively binding to and degrading the mRNA encoding the immediate-early 2 protein of CMV. This mechanism effectively inhibits viral replication, making Fomivirsen a valuable reagent for studying CMV retinitis and other associated CMV diseases. Its application is pertinent in research aimed at understanding CMV pathogenesis and developing therapeutic interventions.
Chemical Information
Catalog NumA50660
M. Wt6682.40
FormulaC204H263N63O114P20S20
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.144245-52-3
SynonymsISIS-2922
SMILES[Fomivirsen]
Biological Activity
DescriptionFomivirsen is an antisense phosphorothioate oligonucleotide that acts as a cytomegalovirus (CMV) inhibitor by selectively binding to and degrading the mRNA encoding the immediate-early 2 protein of CMV. This mechanism effectively inhibits viral replication, making Fomivirsen a valuable reagent for studying CMV retinitis and other associated CMV diseases. Its application is pertinent in research aimed at understanding CMV pathogenesis and developing therapeutic interventions.
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