Product Data Sheet

NS2B/NS3-IN-2

Catalog No. A50691

main product photo
NS2B/NS3-IN-2 is a potent inhibitor of the dengue virus (DENV) NS2B/NS3 protease, demonstrating an IC50 of 6.0 nM and a Ki of 0.66 µM. This covalent inhibitor exhibits no cytotoxicity and significantly enhances cell survival rates, making it an important tool for research in dengue virus therapeutics and antiviral development.
Chemical Information
Catalog NumA50691
M. Wt463.51
FormulaC24H21N3O5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3010940-08-3
Synonyms
SMILESO=S(C(C=C1)=CC=C1OCC)(N2N=C(C=C2N)OC(C3=CC=C(C=C3)C4=CC=CC=C4)=O)=O
Biological Activity
DescriptionNS2B/NS3-IN-2 is a potent inhibitor of the dengue virus (DENV) NS2B/NS3 protease, demonstrating an IC50 of 6.0 nM and a Ki of 0.66 µM. This covalent inhibitor exhibits no cytotoxicity and significantly enhances cell survival rates, making it an important tool for research in dengue virus therapeutics and antiviral development.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.