Product Data Sheet
BP13944
Catalog No. A50711
BP13944 is a small molecule inhibitor that targets the dengue virus (DENV) by inhibiting its NS3 protease. It demonstrates significant antiviral activity, effectively suppressing the replication of all four DENV serotypes with an EC50 value of 1.03±0.09 μM, while showing no toxicity to host cells. Notably, the presence of the E66G mutation in the NS3 protease confers resistance to BP13944. As a promising candidate for dengue virus intervention, BP13944 represents a potential therapeutic agent in the absence of effective vaccines or treatments for dengue.
Chemical Information
| Catalog Num | A50711 |
|---|---|
| M. Wt | 410.47 |
| Formula | C20H44BrNO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1622060-51-8 |
| Synonyms | |
| SMILES | CCCCCCCCCCCCCCCC[N+](CO)(CC)CO.[Br-] |
Biological Activity
| Description | BP13944 is a small molecule inhibitor that targets the dengue virus (DENV) by inhibiting its NS3 protease. It demonstrates significant antiviral activity, effectively suppressing the replication of all four DENV serotypes with an EC50 value of 1.03±0.09 μM, while showing no toxicity to host cells. Notably, the presence of the E66G mutation in the NS3 protease confers resistance to BP13944. As a promising candidate for dengue virus intervention, BP13944 represents a potential therapeutic agent in the absence of effective vaccines or treatments for dengue. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
