Product Data Sheet
ST-148
Catalog No. A50714
ST-148 is a novel small molecule compound that acts as a potent inhibitor of all four serotypes of the dengue virus. In studies using a nonlethal AG129 mouse model, ST-148 significantly decreased viremia and viral load in key organs, while also showing a tendency to reduce plasma cytokine levels. The mechanism of action involves direct interaction with the dengue virus capsid protein, indicating that ST-148 interferes with specific stages of the viral replication cycle, which may provide avenues for therapeutic development against dengue virus infections.
Chemical Information
| Catalog Num | A50714 |
|---|---|
| M. Wt | 421.54 |
| Formula | C21H19N5OS2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 400863-77-6 |
| Synonyms | |
| SMILES | O=C(NC1=NN=C(S1)C2=CC=CC=C2)C3=C(C4=CC5=C(N=C4S3)CCCCC5)N |
Biological Activity
| Description | ST-148 is a novel small molecule compound that acts as a potent inhibitor of all four serotypes of the dengue virus. In studies using a nonlethal AG129 mouse model, ST-148 significantly decreased viremia and viral load in key organs, while also showing a tendency to reduce plasma cytokine levels. The mechanism of action involves direct interaction with the dengue virus capsid protein, indicating that ST-148 interferes with specific stages of the viral replication cycle, which may provide avenues for therapeutic development against dengue virus infections. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
