Product Data Sheet
NS2B/NS3-IN-9
Catalog No. A50735
NS2B/NS3-IN-9 is a non-competitive inhibitor targeting the NS2B-NS3 protease of Orthoflavivirus, demonstrating broad-spectrum antiviral activity. It exhibits IC50 values of 2.4 μM, 7.2 μM, and 1.9 μM against the Dengue virus DENV2, West Nile virus WNV, and Zika virus ZIKV, respectively. Additionally, NS2B/NS3-IN-9 shows cellular EC50 values of 4.1 μM for DENV2, 4.9 μM for WNV, and 5.0 μM for ZIKV, while exhibiting minimal toxicity to host cells. This compound is suitable for research applications focused on inhibiting Orthoflavivirus infections.
Chemical Information
| Catalog Num | A50735 |
|---|---|
| M. Wt | 653.94 |
| Formula | C34H67N7O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 812683-94-6 |
| Synonyms | |
| SMILES | CCCCCCCCCCCCCCCC(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N)=O)CCCCN)=O)C)=O)C)=O)CCCCN)=O |
Biological Activity
| Description | NS2B/NS3-IN-9 is a non-competitive inhibitor targeting the NS2B-NS3 protease of Orthoflavivirus, demonstrating broad-spectrum antiviral activity. It exhibits IC50 values of 2.4 μM, 7.2 μM, and 1.9 μM against the Dengue virus DENV2, West Nile virus WNV, and Zika virus ZIKV, respectively. Additionally, NS2B/NS3-IN-9 shows cellular EC50 values of 4.1 μM for DENV2, 4.9 μM for WNV, and 5.0 μM for ZIKV, while exhibiting minimal toxicity to host cells. This compound is suitable for research applications focused on inhibiting Orthoflavivirus infections. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
