Product Data Sheet

BTA-188

Catalog No. A50806

main product photo
BTA-188 is a pyridazinyl oxime ether that functions as a potent antiviral agent, specifically targeting rhinoviruses and enterovirus 71. It demonstrates remarkable efficacy with an IC50 of 0.8 nM and IC90 of 11 nM against HRV-2, while effectively inhibiting enterovirus replication with an IC50 of 82 nM and an IC90 of 109 nM. BTA-188 holds potential as a chemotherapeutic candidate for treating infections associated with the Picornaviridae family of viruses.
Chemical Information
Catalog NumA50806
M. Wt368.47
FormulaC21H28N4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.314062-80-1
Synonyms
SMILESCCO/N=C/C(C=C1)=CC=C1OCCC(CC2)CCN2C3=NN=C(C)C=C3
Biological Activity
DescriptionBTA-188 is a pyridazinyl oxime ether that functions as a potent antiviral agent, specifically targeting rhinoviruses and enterovirus 71. It demonstrates remarkable efficacy with an IC50 of 0.8 nM and IC90 of 11 nM against HRV-2, while effectively inhibiting enterovirus replication with an IC50 of 82 nM and an IC90 of 109 nM. BTA-188 holds potential as a chemotherapeutic candidate for treating infections associated with the Picornaviridae family of viruses.
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