Product Data Sheet
VNRX-9945
Catalog No. A50938
VNRX-9945 is a potent capsid assembly modulator targeting Hepatitis B Virus (HBV) with an EC50 of 2.6 nM. It exhibits broad antiviral activity against multiple HBV genotypes in vitro, demonstrating its effectiveness in diverse biological contexts. Additionally, VNRX-9945 shows favorable pharmacokinetic properties across various species and has demonstrated significant antiviral efficacy in adeno-associated virus mouse models of HBV infection, making it a valuable tool for HBV research and therapeutic development.
Chemical Information
| Catalog Num | A50938 |
|---|---|
| M. Wt | 429.48 |
| Formula | C23H28FN3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2396680-45-6 |
| Synonyms | |
| SMILES | O=C(C1=C(C)N(C)C(C(C(N[C@H]2CC[C@@H](O)CC2)=O)=O)=C1C)NC3=CC=C(F)C(C)=C3 |
Biological Activity
| Description | VNRX-9945 is a potent capsid assembly modulator targeting Hepatitis B Virus (HBV) with an EC50 of 2.6 nM. It exhibits broad antiviral activity against multiple HBV genotypes in vitro, demonstrating its effectiveness in diverse biological contexts. Additionally, VNRX-9945 shows favorable pharmacokinetic properties across various species and has demonstrated significant antiviral efficacy in adeno-associated virus mouse models of HBV infection, making it a valuable tool for HBV research and therapeutic development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
