Product Data Sheet

Yhhu6669

Catalog No. A51016

main product photo
Yhhu6669 is a potent inhibitor of Hepatitis B Virus (HBV), targeting HBV DNA replication. It functions by inducing the formation of DNA-free capsids, effectively reducing HBV levels. In preclinical studies using AAV/HBV-infected mouse models, Yhhu6669 demonstrated significant decreases in both HBV DNA and HBcAg. Additionally, it exhibits favorable pharmacokinetic properties, making it a valuable tool for research in HBV therapeutic development.
Chemical Information
Catalog NumA51016
M. Wt563.02
FormulaC29H28ClFN6O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2569526-80-1
Synonyms
SMILESClC1=C(NCCCOC([C@@H](N)C(C)C)=O)N=C(F)C(C(C2=C3C=CC=C2)=NN(CC4=CC=C(C#N)C=C4)C3=O)=C1
Biological Activity
DescriptionYhhu6669 is a potent inhibitor of Hepatitis B Virus (HBV), targeting HBV DNA replication. It functions by inducing the formation of DNA-free capsids, effectively reducing HBV levels. In preclinical studies using AAV/HBV-infected mouse models, Yhhu6669 demonstrated significant decreases in both HBV DNA and HBcAg. Additionally, it exhibits favorable pharmacokinetic properties, making it a valuable tool for research in HBV therapeutic development.
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