Product Data Sheet
Boceprevir-d9
Catalog No. A51127
Boceprevir-d9 is a deuterated form of Boceprevir, a selective and potent inhibitor of the HCV NS3 protease with a Ki value of 14 nM in enzyme assays. It demonstrates an EC90 of 350 nM in cell-based replicon assays, showcasing its efficacy against hepatitis C virus replication. Additionally, Boceprevir has been shown to inhibit SARS-CoV-2 3CLpro activity, making it valuable for research in antiviral drug development and therapeutic applications targeting viral proteases.
Chemical Information
| Catalog Num | A51127 |
|---|---|
| M. Wt | 528.73 |
| Formula | C27H36D9N5O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1256751-11-7 |
| Synonyms | EBP 520-d9; SCH 503034-d9 |
| SMILES | NC(C(C(CC1CCC1)NC([C@@H]2[C@]3([H])[C@@](CN2C([C@H](C(C)(C)C)NC(NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=O)([H])C3(C)C)=O)=O)=O |
Biological Activity
| Description | Boceprevir-d9 is a deuterated form of Boceprevir, a selective and potent inhibitor of the HCV NS3 protease with a Ki value of 14 nM in enzyme assays. It demonstrates an EC90 of 350 nM in cell-based replicon assays, showcasing its efficacy against hepatitis C virus replication. Additionally, Boceprevir has been shown to inhibit SARS-CoV-2 3CLpro activity, making it valuable for research in antiviral drug development and therapeutic applications targeting viral proteases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
