Product Data Sheet
Ledipasvir-d6
Catalog No. A51153
Ledipasvir-d6 is a deuterated form of Ledipasvir, an effective inhibitor of the hepatitis C virus NS5A, exhibiting EC50 values of 34 pM against genotype 1a and 4 pM against genotype 1b replicons. Additionally, Ledipasvir serves as a SARS-CoV 3CLpro inhibitor, with an IC50 of 1.62 μM. This stable isotope is suitable for advanced research applications in virology and drug development, particularly in studies involving metabolic tracing and pharmacokinetics.
Chemical Information
| Catalog Num | A51153 |
|---|---|
| M. Wt | 895.04 |
| Formula | C49H48D6F2N8O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2050041-12-6 |
| Synonyms | GS-5885-d6 |
| SMILES | O=C(OC([2H])([2H])[2H])N[C@H](C(N([C@H](C1=NC=C(C2=CC(C(F)(F)C3=C4C=CC(C5=CC=C6N=C([C@H]7N(C([C@@H](NC(OC([2H])([2H])[2H])=O)C(C)C)=O)[C@]8([H])CC[C@@]7([H])C8)NC6=C5)=C3)=C4C=C2)N1)C9)CC%109CC%10)=O)C(C)C |
Biological Activity
| Description | Ledipasvir-d6 is a deuterated form of Ledipasvir, an effective inhibitor of the hepatitis C virus NS5A, exhibiting EC50 values of 34 pM against genotype 1a and 4 pM against genotype 1b replicons. Additionally, Ledipasvir serves as a SARS-CoV 3CLpro inhibitor, with an IC50 of 1.62 μM. This stable isotope is suitable for advanced research applications in virology and drug development, particularly in studies involving metabolic tracing and pharmacokinetics. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
